chemistry1111 it cannot be B because the question has stated that aldicarb is a reversible inhibitor of acetylcholinesterase. This means it will form weak intermolecular bonds with the the enzyme (not strong covalent bonds like irreversible inhibitors), allowing it to detach from the active site (reversible = non-permanent). B says it strongly binds to the active site of acetylcholinesterase, which is therefore incorrect. A is also incorrect because the question already states that it is reversible, not permanent/irreversible. C is incorrect because inhibitors prevent the substrate from being catalysed by the enzyme, meaning the rate of the breakdown of acetylcholine cannot increase. D is correct because it will reduce the activity of acetylcholinesterase, binding to its active site and "reducing the number of active sites for acetylcholine to bind to". Hope that helps!